Table 2.

Baseline mean arterial pressure (MAP) and heart rate (HR) in 2-kidney, 1-clip (2K1C) rats, and normotensive (NT) rats that received intra-NTS injections of AAV2-CBA-eGFP or AAV2-CBA-MIF vectors

Group	n	MAP (mm Hg)	HR (bpm)
NT-GFP	12	100 ± 2	350 ± 12
NT-MIF	9	102 ± 2	355 ± 19
2K1C-GFP	12	189 ± 7*	392 ± 13
2K1C-MIF	6	153 ± 6*#	367 ± 13

MAP and HR recordings were performed 7 weeks after 2K1C or sham surgery (NT group) and 4 weeks after GFP or MIF transduction in the NTS. Data are expressed as mean ± SEM; *P < 0.05 vs. NT groups; ^#P < 0.05 vs. 2K1C-GFP; 1-way ANOVA, followed by Student–Newman–Keuls test; n = number of animals used in the baroreflex data (pharmacologically induced baroreflex and spontaneous baroreflex). Abbreviations: ANOVA, analysis of variance; MIF, macrophage migration inhibitory factor; NTS, nucleus of the solitary tract.