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. 2018 Mar 20;10:33. doi: 10.1186/s13195-018-0362-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Kaplan–Meier survival curves for probability of conversion to AD according to different MCI biomarker-based subgroups. Number of individuals at risk at each time interval shown below the graphs. MCI subgroups determined taking into account CSF t-Tau and p-Tau levels and either Aβ42 (a) or the Aβ42/40 ratio (b). Log-rank (Mantel–Cox) p < 0.001 for both. AD Alzheimer’s disease, LL low-AD likelihood, HL high-AD likelihood, IAP isolated amyloid pathology, SNAP suspected non-Alzheimer pathology