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. 2018 Feb 1;14(3):532–539. doi: 10.1080/21645515.2017.1419109

Figure 1.

Figure 1.

Modified sequence in HA and NA of reassortant viruses. (A) HA cleavage site sequence. LAPI–HA7: consensus sequence of low pathogenic avain influenza viruses H7 (reference to the sequence in NCBI gene bank, Accession Number: APR73185, AJU15335, AKI82233, APW83929, AHL21384, AJE61993, ANH96462, ALR82230, AJU15321, APW83918); RG-17SF003HA: sequence of (6+2) reassortant H7N9 virus by reverse technology with deletion of KRTA; Wild-17SF003HA: sequence of wild-type virus A/Guangdong/17SF003/2016; ↓: proteolytic cleavage site. (B) Part of amino acid sequence associated with resistance to neuraminidase inhibitors (N2 numbering: 291–293 position). Wild—17SF003NA: wild-type 17SF003 virus containing NA-292K/R; RG-17SF003NA: (6+2) reassortant 17SF003 virus containing NA-292R. Change sequences were in bold.