Table 1.
Monoclonal antibodies |
Polyclonal antibodies |
High cost | Low cost |
Hybridoma-derived | Animal-derived |
Low scale-up | High scale-up |
Single epitope specificities | Multiple epitope specificities |
Defined purity | Undefined purity |
Broadly neutralizing | Broadly neutralizing |
Selection of resistant mutants | Less selection of resistant mutants |
Initial efficacy | Long-term efficacy |