TABLE 2.
Aerotolerance, temperature viability, and IL-8 production stimulated by heat-treated bacteria of NEC and control strains in Caco-2 cells
| Strain group (n) | Aerotolerancea (95% CIb) (log10 CFU/ml) | Reduction in viable bacteriaa (95% CI) (log10 CFU/ml) at temp: |
IL-8 production by heat-treated bacteriac (95% CI) (pg/ml) | |
|---|---|---|---|---|
| 30°C | 50°C | |||
| Control (29) | −4.08 (−4.78 to −3.37) | −0.85 (−1.18 to −0.52) | −5.85 (−6.42 to −5.27) | 43.8 (31.7 to 56.0) |
| NEC (30) | −2.99 (−3.62 to −2.35) | −0.46 (−0.82 to −0.10) | −5.02 (−5.84 to −4.21) | 62.4 (46.1 to 78.7) |
| P value | 0.01d | 0.03d | 0.19 | 0.03d |
a
Average differences in cell count of the tested strains compared to the experimental control strains.
b
95% CI, 95% confidence interval.
c
Average IL-8 level of the tested strains.
d
Significant difference between the NEC and control strains (Wilcoxon-Mann and Whitney U test [P < 0.05]).