Table 3.

Selected Examples of Potential Influences of Biologic Aging-Related Mechanisms on Types of Resilience

Mechanisms	Type of Resilience Affected
Cell senescence	Immune responses, cancer chemotherapy tolerance, wound healing
Impaired stem/progenitor cell function	Resistance to infections, wound healing, cancer chemotherapy tolerance
Dysregulation of inflammatory factors	Infection resistance and recovery, wound healing, avoiding postsurgical MI, cancer chemotherapy intolerance
Inadequate DNA repair	Cancer chemotherapy tolerance
Impaired mitochondrial function	Ability to meet bioenergetic demands posed by stressors (eg, for averting falls, mounting febrile responses)