Table 3.

Adjusted Associations Between Adiposity and Global Cognition at ages 65 and 75 years

	Model 1 (Separate Models, Individual Measures)			Model 2 (Parsimonious Collective Multiple Regression)
	Age = 65	Age = 75	Age Interaction	Age = 65	Age = 75	Age Interaction
WC	−0.057 p = .027	−0.012 p = .669	p = .112	−0.117 p = .008	−0.117 p = .008
	(−0.107, −0.006)	(−0.069, 0.044)		(−0.205, −0.030)	(−0.205, −0.030)
BMI	−0.035 p = .161	0.041 p = .186	p = .005	−0.003 p = .960	0.075 p = .216	p = .004
	(−0.084, 0.014)	(−0.020, 0.102)		(−0.110, 0.104)	(−0.044, 0.193)
SAT	−0.014 p = .600	0.056 p = .067	p = .005	0.093 p = .036	0.093 p = .036
	(−0.066, 0.038)	(−0.004, 0.115)		(0.006, 0.180)	(0.006, 0.180)
VAT	−0.037 p = .131	−0.016 p = .549	p = .420
	(−0.084, 0.011)	(−0.070, 0.037)

Note: β, p value, 95% CI. All predictors are standardized. See Supplementary Table 4 for details on all interaction models. VAT = Visceral adipose tissue.

Model 1: Separate models included each adiposity measure, age, age-by-adiposity interaction, sex, education, and smoking status.

Model 2: Waist circumference (WC) + body mass index (BMI) + age + age-by-BMI interaction + subcutaneous adipose tissue (SAT), sex, education, and smoking status.