Table 3.
Age Correlation With the BOLD Signal in the Central Olfactory System
| Condition | Area | MNI Coordinates (mm) | Cluster Size (voxel) | Cluster Level | Voxel Level | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| x | y | z | p FWE-corr | p uncorr | p FWE-corr | p uncorr | t Value | |||
| Odor-sniff | R-DLPFC | 38 | 44 | 28 | 51 | .360 | .437 | .173 | .000 | 4.01 |
| R-DLPFC | 48 | 16 | 40 | 107 | .231 | .257 | .271 | .000 | 3.80 | |
| L-OFC/L-insula | −40 | 16 | −6 | 79 | .286 | .330 | .287 | .000 | 3.78 | |
| L-DLPFC | −36 | 32 | 32 | 32 | .427 | .545 | .458 | .001 | 3.53 | |
| Odorless-sniff | L-OFC/L-insula | −42 | 28 | 2 | 95 | .245 | .284 | .278 | .000 | 3.77 |
Note: The secondary olfactory structures showed significant negative aging effect on the olfactory activation signal (multiple regression, p < .001, corrected with cluster size ≥28 voxels). Coordinates are given in the left-posterior-inferior system in the Montreal Neurological Institute (MNI) brain template space. L = left; R = right. DLPFC = dorsolateral prefrontal cortex; FWE = family-wise error; OFC = orbitofrontal cortex. corr = corrected; uncorr = uncorrected.