Table 3.
Bias Corrected Bootstrapped* Estimates and Confidence Intervals** for the Indirect Effect of Pain on Gait Speed Adjusting for Covariates.***
| Presence of pain | Global pain index | |||||||
|---|---|---|---|---|---|---|---|---|
| Effect | Error | Lower bound | Upper bound | Effect | Error | Lower bound | Upper bound | |
| White matter macrostructure (WMH) | −.0064 | .0029 | −.0132 | −.0019 | −.0034 | .0014 | −.0070 | −.0011 |
| White matter microstructure (FA) | .0031 | .0022 | .0002 | .0092 | .0012 | .0010 | .0000 | .0044 |
| Gray matter microstructure (MD) | .0000 | .0017 | −.0041 | .0032 | .0002 | .0008 | −.0011 | .0024 |
Note: BMI = body mass index; FA = fractional anisotropy; MD = mean diffusivity; NSAID = nonsteroidal anti-inflammatory medications; WMH = white matter hyperintensities. The bold value signifies p < .05.
*n = 1,000 bootstrap samples.
**95% Bootstrapped confidence intervals.
***Adjusted for age, gender, BMI, NSAID medication use, and brain atrophy.