Table 1. Patients’ Characteristics.
N | 235 |
Age (y/o) | 67.4 ± 11.1 |
Gender (male/female) | 109/126 |
Etiology (HCV/HBV/alcohol/NASH/others) | 148/27/25/15/20 |
BMI (kg/m2) | 23.8 ± 4.1 |
Daily alcohol intake (none/< 60 g/≥ 60 g) | 179/25/23 |
Platelets count (× 103/mm3) | 102.9 ± 64.4 |
AST (IU/L) | 52.0 ± 32.1 |
ALT (IU/L) | 41.8 ± 29.4 |
Albumin (g/dL) | 3.67 ± 0.53 |
Total bilirubin (mg/dL) | 1.10 ± 0.53 |
Prothrombin time (international normalized ratio) | 1.13 ± 0.18 |
Creatinine (mg/dL) | 0.90 ± 1.30 |
BUN (mg/dL) | 16.4 ± 10.8 |
BCAA-to-tyrosine ratio (BTR) | 3.97 ± 1.77 |
Child-Pugh score | 6.03 ± 1.15 |
Ammonia (µg/dL) | 48.7 ± 33.5 |
Total cholesterol (mg/dL) | 157.9 ± 33.5 |
Triglycerides (mg/dL) | 93.4 ± 49.6 |
Fasting blood glucose (mg/dL) | 114.8 ± 31.7 |
HbA1c (%) | 5.50 ± 1.03 |
HOMA-IR | 5.71 ± 8.86 |
Zinc (µg/dL) | 64.1 ± 15.8 |
Ferritin (ng/mL) | 168.2 ± 522.0 |
AFP (ng/mL) | 18.1 ± 37.4 |
Edema, ascites (+/-) | 46/187 |
Administration of diuretics (+/-) | 78/157 |
Administration of BCAA (+/-) | 78/157 |
Administration of oral DM agents (+/-) | 56/179 |
Administration of insulin (+/-) | 22/213 |
Values are expressed as mean ± SD. y/o: years old; HCV: hepatitis C virus; HBV: hepatitis B virus; NASH: non-alcoholic steatohepatitis; BMI: body mass index; AST: aspartate aminotransferase; ALT: alanine aminotransferase; BUN: blood urea nitrogen; BCAA: branched-chain amino acid; HOMA-IR: homeostasis model assessment-insulin resistance; AFP: alpha-fetoprotein; DM: diabetes mellitus.