Table 2.

Subject enrollment in the pooled clinical trials of lacosamide monotherapy for diabetic neuropathic pain, presented by age (<65 years or ≥65 years)

	Study ID					Pooled
	SP614	SP742	SP743	SP768	SP874
Total (SS)	119	370	357	468	549	1,863
≥65 years						502 (26.9%)
<65 years						1,361 (73.1%)
Placebo	59	93	74	65	179	470
≥65 years						113 (24.0%)
<65 years						357 (76.0%)
Lacosamide 200 mg/day	n/a	93	n/a	141	n/a	234
≥65 years						83 (35.5%)
<65 years						151 (64.5%)
Lacosamide 400 mg/day	60	91	150	125	370	796
≥65 years						215 (27.0%)
<65 years						581 (73.0%)
Lacosamide 600 mg/day	n/a	93	133	137	n/a	363
≥65 years						91 (25.1%)
<65 years						272 (74.9%)

n/a, not applicable; SS, safety set.