Skip to main content
. 2017 Dec 30;10:331–348. doi: 10.1016/j.omtn.2017.12.014

Figure 2.

Figure 2

Overexpression of miR-544a/miR-379 Suppressed Angiogenesis of U87 Glioma

(A and B) The relative expressions of miR-544a (A) and miR-379 (B) in AECs and GECs were detected by qRT-PCR. U6 was used as an inner control. Data represent means ± SD (n = 5, each group). *p < 0.05 versus AECs group. (C and D) The effects of miR-544a (C) and miR-379 (D) on the viability of GECs were determined by CCK-8 assay. Values are means ± SD (n = 5, each group). **p < 0.01 versus miR-544a/miR-379 (+) NC group; ##p < 0.01 versus miR-544a/miR-379 (−) NC group. (E and F) The effects of miR-544a (E) and miR-379 (F) on the migration of GECs by Transwell assay. Values are means ± SD (n = 5, each group). **p < 0.01 versus miR-544a/miR-379 (+) NC group; ##p < 0.01 versus miR-544a/miR-379 (−) NC group. Scale bar represents 30 μm. (G and H) The effects of miR-544a (G) and miR-379 (H) on the tube formation of GECs were evaluated by Matrigel tube formation assay (black arrows, tube structures; gray arrows, tube branches). Values are means ± SD (n = 5, each group). *p < 0.05, **p < 0.01 versus miR-544a/miR-379 (+) NC group; #p < 0.05, ##p < 0.01 versus miR-544a/miR-379 (−) NC group. Scale bar represents 30 μm.