Table 3.

Primary composite outcome of survival free of major neurosensory impairment at 2–5 years corrected gestational age

	Probiotic group n=373	Placebo group n=362	Relative risk (95% CI)	P value
Survival without major neurosensory impairment* N (%)	281 (75.3)	271 (74.9)	1.01 (0.93 to 1.09)	0.88
Subgroup analyses:
Gestation				0.08†
<28 weeks, n (%)  ≥28 weeks, n (%)	104 (63.0) 177 (85.1)	118 (69.0) 153 (80.1)	0.91 (0.78 to 1.07) 1.06 (0.97 to 1.16)	0.25 0.19
Birth weight				0.62†
<1000 g, n (%)  ≥1000 g, n (%)	116 (65.5) 165 (84.2)	113 (66.5) 158 (82.3)	0.99 (0.85 to 1.15) 1.02 (0.94 to 1.12)	0.85 0.62

*Major neurosensory impairment=motor impairment AND/OR cognitive impairment AND/OR blindness AND/OR deafness.

†Interaction P value.