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Somatic copy number alteration events independently associated with mutant-allele tumor heterogeneity (MATH) with P < 0.05 in the logistic regression adjusting for multiple testing by Benjamini–Hochberg approach in the training cohort. Red indicates low MATH group, green indicates intermediate MATH group and blue indicates high MATH group. Alteration rate is displayed along the vertical axis, while the direction of arrow represents SCNA gain (above 0) or loss (below 0).
