Table 5.
SNP function prediction
| SNP | Gene | Position | Promoter histone marks | Enhancer histone marks | DNase | Motifs changed | eQTL |
|---|---|---|---|---|---|---|---|
| rs884904 | EGFR | 3′ near gene | GI | GI | 6 altered motifs | ||
| rs7809332 | EGFR | 3′ near gene | 8 altered motifs | ||||
| rs6941183 | ADGRF1 | Intronic | 10 altered motifs | ADGRF1 | |||
| rs1226500 | ADGRF1 | 3′ near gene | 8 tissues | 8 tissues | 7 altered motifs | ||
| rs3815188 | NOTCH3 | Synonymous | IPSC, MUS | Hic1 | ILVBL | ||
| rs2238643 | NOTCH3 | Intronic | IPSC | Ik-3, NRSF, SMC3 | ILVBL | ||
| rs2118610 | SMAD3 | Intronic | LNG | 19 tissues | 6 tissues | Foxp1 | SMAD3 |