Table 2.
Top 10 pathways determined from metabolomic and proteomic data results
| Rank | Pathway | No. of overlapping genes | No. of genes in pathway | p-Value | Q-Value | No. of overlapping metabolites |
|---|---|---|---|---|---|---|
| 1 | Metabolism | 216 | 1427 (1485) | 8.51E-23 | 1.66E-19 | 39 |
| 2 | Cytoplasmic ribosomal proteins | 44 | 88 (88) | 1.62E-25 | 6.32E-22 | 0 |
| 3 | Glucose metabolism | 32 | 67 (70) | 3.95E-18 | 2.21E-15 | 5 |
| 4 | Superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle | 28 | 48 (52) | 4.42E-19 | 5.33E-16 | 3 |
| 5 | Warburg effect | 27 | 45 (45) | 6.82E-19 | 5.33E-16 | 4 |
| 6 | Ribosome––Homo sapiens (human) | 46 | 134 (135) | 2.31E-18 | 1.50E-15 | 0 |
| 7 | Translation | 59 | 205 (217) | 6.21E-19 | 5.33E-16 | 0 |
| 8 | SRP-dependent cotranslational protein targeting to membrane | 47 | 154 (164) | 2.01E-16 | 5.24E-14 | 0 |
| 9 | Eukaryotic translation elongation | 46 | 138 (148) | 8.77E-18 | 4.28E-15 | 0 |
| 10 | Gluconeogenesis | 19 | 32 (33) | 1.50E-13 | 2.34E-11 | 5 |