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. 2016 Jul 2;18(5):735–743. doi: 10.1093/bib/bbw057

Figure 4.

Figure 4

The number and rate of false positives on the basis of mock comparisons generated using two data sets: number of false positives (A) in LTHSC data by Kowalczyk et al. [16] and (B) in ILC data by Björklund et al. [17], and false-positive rate (C) in LTHSC data and (D) in ILC data. In both mock comparisons, DE genes were detected between two artificially constructed subsets of cells from the same population, in which no significant detections were expected. The points correspond to 10 randomly generated mock data sets. Limma could not be used with LTHSC data and DESeq could not be used with ILC data. In ILC data, Limma had high number of false positives and false positive rate compared with the other methods and therefore it was visualized separately. When there are <10 points visible, some of the points are overlapping. A colour version of this figure is available at BIB online: https://academic.oup.com/bib.