Figure 2.
DNA methylation profiles of NLT, non-cancerous liver tissue showing non-alcoholic steatohepatitis (NASH-N), and non-cancerous liver tissue showing chronic hepatitis or cirrhosis associated with HBV or HCV infection (viral-N). PCA was performed using the 3331 probes showing significant DNA methylation alterations in NASH-N samples relative to NLT samples, in NLT samples (n = 55, black), NASH-N samples (n = 113, red) and viral-N samples (n = 37, blue).