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. 2017 Jan 25;38(3):261–270. doi: 10.1093/carcin/bgx005

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© The Author 2017. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — DNA methylation levels and mRNA expression levels for representative probes that were included in the 80 NASH-specific probes (Supplementary Table 8, available at Carcinogenesis Online) for which DNA methylation alterations were inherited by NASH-related hepatocellular carcinoma (HCC) (NASH-T) and showed significant differences in DNA methylation levels between NASH-T samples and HCC associated with HBV or HCV infection (viral-T). (A) DNA methylation levels in NASH-T samples (n = 22) and viral-T samples (n = 37). Each gene symbol is shown under the Infinium probe ID. (B) Levels of mRNA expression for the WHSC1 gene in NASH-T samples (n = 21) and viral-T samples (n = 31).