Table 1.
Patient Characteristics (n = 245), Univariate Analysis Results*
| # Patients (%) | Any Complication | Wound Complication | Fistula | Readmission | |
|---|---|---|---|---|---|
| Age (mean) | 64.1 | 0.99 (0.97-1.02) | 1.01 (0.98-1.04) | 1.02 (0.98-1.06) | 1.01 (0.97-1.04) |
| Sex | 1.43 (0.76-2.69) | 1.28 (0.62-2.61) | 1.41 (0.61-3.23) | 1.17 (0.49-2.76) | |
| Male | 193 (78.8) | ||||
| Female | 52 (21.2) | ||||
| Primary Tumor Site | |||||
| Larynx | 172 (69.8) | - | - | - | - |
| Pharynx | 57 (23.3) | 1.69 (0.92-3.13) | 1.63 (0.82-3.26) | 2.36 (1.08-5.16) | 1.44 (0.64-3.26) |
| Thyroid/Other | 17 (6.9) | 0.67 (0.21-2.14) | 1.29 (0.39-4.20) | 1.07 (0.23-5.03) | 0.90 (0.19-4.21) |
| Prior Radiation | |||||
| None | 93 (38.0) | - | - | - | - |
| Narrow-field | 39 (15.9) | 0.57 (0.23-1.39) | 0.66 (0.22-1.93) | 1.40 (0.39-5.10) | 0.56 (0.15-2.12) |
| Wide-field | 113 (46.1) | 1.52 (0.85-2.70) | 1.69 (0.87-3.30) | 3.14 (1.28-7.69) | 1.36 (0.62-2.98) |
| Prior partial laryngeal surgery | 30 (12.2) | 0.26 (0.09-0.79) | 0.37 (0.11-1.26) | 0.66 (0.19-2.31) | 0.95 (0.31-2.91) |
| Smoking history | |||||
| Never | 34 (13.9) | - | - | - | - |
| Former | 138 (56.3) | 2.06 (0.83-5.07) | 4.83 (1.10-21.3) | 6.6 (0.86-50.7) | 2.87 (0.64-12.9) |
| Current | 73 (29.8) | 2.4 (0.92-6.24) | 5.63 (1.23-25.8) | 5.24 (0.64-42.7) | 2.84 (0.59-13.6) |
| Alcohol history >2 drinks/day | |||||
| Never | 118 (48.2) | - | - | - | - |
| Former | 59 (24.1) | 1.95 (1.01-3.73) | 1.49 (0.70-3.14) | 1.65 (0.68-4.02) | 1.15 (0.47-2.78) |
| Current | 68 (27.7) | 1.26 (0.67-2.40) | 1.34 (0.65-2.78) | 1.56 (0.66-3.70) | 0.97 (0.40-2.34) |
| Hypoalbuminemia (<3.5g/dL) | 79 (32.2) | 1.31 (0.75-2.28) | 1.10 (0.58-2.10) | 0.86 (0.39-1.89) | 2.77 (1.32-5.78) |
| Hypothyroid (TSH>4.2μIU/mL) | 47 (19.7) | 1.12 (0.58-2.19) | 0.79 (0.36-1.76) | 1.06 (0.43-2.62) | 1.11 (0.45-2.74) |
| Diabetes mellitus | 40 (16.3) | 0.51 (0.23-1.13) | 0.89 (0.38-2.06) | 1.12 (0.43-2.90) | 0.65 (0.22-1.95) |
| Immunosuppression | 36 (14.7) | 0.72 (0.33-1.57) | 0.41 (0.14-1.21) | 0.75 (0.25-2.26) | 0.52 (0.15-1.81) |
Odds Ratio (95% Confidence Interval). Abbreviations: TSH, thyroid stimulating hormone