Table 1. Study population: distribution of cases and controls according to sex, age and smoking status.

		Controls	CRC	High-risk adenoma	Low-risk adenoma	p-value (differences between status groups)
	N	546	383	542	535	0,9981
Sex	female	217 (40%)	151 (39%)	215 (40%)	214 (40%)	0,9725
Age	≤ 40	11 (2%)	8 (2%)	10 (2%)	9 (2%)
	≤ 50	36 (7%)	29 (8%)	37 (7%)	38 (7%)
	≤ 60	134 (25%)	86 (22%)	132 (24%)	132 (25%)
	≤ 70	152 (28%)	111 (29%)	150 (28%)	159 (30%)
	≤ 80	180 (33%)	120 (31%)	186 (34%)	182 (34%)
	≤ 90	33 (6%)	29 (8%)	27 (5%)	15 (3%)
Smoking	current	57 (10%)	54 (14%)	116 (21%)	93 (17%)	0,00001 ***
	former	163 (30%)	91 (24%)	174 (32%)	159 (30%)
	never	309 (57%)	129 (34%)	233 (43%)	265 (50%)
	missing	17 (3%)	109 (28%)	19 (4%)	18 (3%)