Table 4. Amino acid residues of NKX2.5 and GATA4 present in cutoff value 8.0 Å (cut off taken through pymol).
| MOTIFs | NKX2.5 | GATA4 | ||||||
|---|---|---|---|---|---|---|---|---|
| Residues | PI | MT | PTM | Residues | PI | MT | PTM | |
| Binding Region 2(BR2) | I255 | |||||||
| V14 | K256 | |||||||
| K15 | K15 | K 15 I | P257 | |||||
| D16 | D16 | D 16 N | Q258 | Q258 | ||||
| I17 | R259 | R259 | ||||||
| L18 | R260 | R260 | R260Q | |||||
| N19 | N19 | N19S | L261 | L261P | ||||
| L20 | S262 | S262 | ||||||
| E21 | E 21 Q | A263 | ||||||
| Q22 | Q22 | Q 22 K/P/R | S264 | S264 | ||||
| Q23 | R265 | |||||||
| Q24 | R265 | R 265 TER* | ||||||
| Binding Region 1(BR1) | R25 | R25 | R 25 C | N239 | N239D | |||
| S26 | A240 | |||||||
| L27 | C241 | |||||||
| A28 | G242 | |||||||
| A29 | L243 | |||||||
| A30 | Y244 | Y244 | Y244C | Y244 | ||||
| G31 | H245 | |||||||
| E32 | E32 | E 32 K | K246 | |||||
| L33 | M247 | M247T | ||||||
| S34 | N248 | N248S | ||||||
| A35 | G249 | |||||||
| R36 | R36 | R 36 S | I250 | |||||
| L37 | N251 | |||||||
| E38 | R252 | R252 | R252P | |||||
| A39 | P253 | |||||||
| T40 | L254 | |||||||
| I255 | I255T | |||||||
Residues participated in direct polar interaction, mutations, and PTM localize in the interaction zone are listed. PI = Polar Interactions, MT = Mutations. Bold amino acids are those, which are identified by this work.