Table 1. Relationships of miR-630 and Bcl-2 expression levels with clinico-pathological parameters, and the association between miR-630 and Bcl-2 expression levels in lung cancer patients.
miR-630 | Bcl-2 | |||||||
---|---|---|---|---|---|---|---|---|
No. | Low | High | P | Low | High | P | ||
Age | ||||||||
< 65 | 57 | 28(49.1) | 29(50.9) | 0.851 | 24 (42.1) | 33 (57.9) | 0.572 | |
≥ 65 | 57 | 29(50.9) | 28(49.1) | 27 (47.4) | 30 (52.6) | |||
Gender | ||||||||
Female | 38 | 20(52.6) | 18(47.4) | 0.691 | 14 (36.8) | 24 (63.2) | 0.231 | |
Male | 76 | 37(48.7) | 39(51.3) | 37 (48.7) | 39 (51.3) | |||
Smoking status | ||||||||
Nonsmokers | 55 | 29(52.7) | 26(47.3) | 0.574 | 22 (40.0) | 33 (60.0) | 0.326 | |
Smokers | 59 | 28(47.5) | 31(52.5) | 29 (49.2) | 30 (50.8) | |||
Tumor type | ||||||||
Adenocarcinoma | 56 | 25(44.6) | 31(55.4) | 0.261 | 22 (39.3) | 34 (60.7) | 0.250 | |
Squamous | 58 | 32(55.2) | 26(44.8) | 29 (50.0) | 29 (50.0) | |||
Stage of Cancer | ||||||||
1 | 43 | 16(37.2) | 27(62.8) | 0.034 | 21 (48.8) | 22 (51.2) | 0.493 | |
2–3 | 71 | 41(57.7) | 30(42.3) | 30 (42.3) | 41 (57.7) | |||
miR-630 | ||||||||
Low | 57 | 18 (31.6) | 39 (68.4) | 0.005 | ||||
High | 57 | 33 (57.9) | 24 (42.1) |