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. 2018 Feb 14;9(17):13859–13869. doi: 10.18632/oncotarget.24492

Table 1. Incidence of carcinoma and quantitative evaluation of neoplastic lesions in prostates of TRAP rats treated C21.

	No. of rat	Ventral				Lateral
		Incidence of carcinoma	% of lesions in prostate			Incidence of carcinoma	% of lesions in prostate
		Incidence of carcinoma	LG-PIN	HG-PIN	Adenocarcinoma	Incidence of carcinoma	LG-PIN	HG-PIN	Adenocarcinoma
Control	12	12 (100%)	6.9 ± 2.5	82.9 ± 5.4	10.3 ± 4.4	12 (100%)	12.0 ± 11.0	79.6 ± 10.9	8.4 ± 4.0
C21 1 mg/kg/day	12	12 (100%)	16.7 ± 4.8^****	73.9 ± 4.6	9.4 ± 3.9	10 (83%)	12.6 ± 9.4	79.5 ± 13.1	7.9 ± 7.4
C21 2 mg/kg/day	12	12 (100%)	14.1 ± 3.1^***	80.8 ± 3.9	5.2 ± 4.0^*	7 (58%)^*	20.2 ± 11.0^***	77.0 ± 9.7	2.8 ± 4.0^*

^*p < 0.05, ^***p < 0.001, ^****p < 0.001: significantly different from control group.