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. 2017 Dec 26;9(17):13911–13919. doi: 10.18632/oncotarget.23744

Table 2. Methodological quality of included studies.

Newcastle–Ottawa Scale (NOS) Quality Assessment Table
Study Selection Comparability Exposure/Outcome Total Star
Dong-liang Chen [13] ++++ + +++ 8
Lei Ma [19] ++++ + ++ 7
Peng Song [22] ++++ + +++ 8
Wei Wei [23] +++ + +++ 7
G.-L. LI [15] ++++ + +++ 8
Xiaoliang Wu [24] ++++ + +++ 8
Yichao Mo [21] ++++ + ++ 7
Weijie Ma [20] ++++ + +++ 8
Reiko Kobayashi [14] ++++ + ++ 7

A star system was used to allow a semiquantitative assessment of study quality. A study could be awarded a maximum of 1 star for each numbered item within the selection and exposure categories. A maximum of 2 stars could be given for comparability. The NOS ranged from 0 to 9 stars. Studies achieved 7 were considered as high-quality ones, 4 to 6 stars were medium-quality studies, and < 4 stars were poor-quality studies.