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. 2018 Jan 11;9(17):13934–13947. doi: 10.18632/oncotarget.24172

Table 3. Summary of the association of C-reactive protein/albumin ratio and clinopathological parameters in solid tumors.

Category n Model OR (95% CI) Z P Heterogeneity
I2 Ph
Histologic grade (poor vs. well or moderate) 7 (1983) Fixed 1.47 (1.14–1.90) 2.97 0.003 0.0% 0.654
Clinical stage (III or IV vs. I or II) 12 (6279) Random 3.20 (2.37–4.32) 7.58 < 0.001 71.8% < 0.001
Tumor depth (T3+T4 vs. T1+T2) 7 (4367) Random 2.57 (1.52–4.34) 3.52 < 0.001 80.0% < 0.001
Lymph node metastasis (positive vs. negative) 8 (4496) Random 2.25 (1.62–3.14) 4.83 < 0.001 60.5% 0.013
Distant metastasis (positive vs. negative) 4 (1266) Random 3.97 (1.56–10.09) 2.89 0.004 75.8% 0.006
Smoking status (ever vs. never) 5 (3761) Fixed 1.16 (1.00–1.34) 1.95 0.052 45.9% 0.117

P denotes P value for statistical significance based on Z test; Ph denotes P value for heterogeneity based on Q test. OR odds ratio; CI confidence interval.