Table 2. Characteristics of the 14 articles on BMI and postoperative survival of RCC.
| Author year country |
Mean/ median age, range |
Follow up year |
Study size |
n | BMI (kg/m2) |
HR (95%CI) | surgical method |
Adjustment factors |
NOS |
|---|---|---|---|---|---|---|---|---|---|
| Sung et al 2012 Korea |
median 54 (34–67) 54 (45–63) 56 (47–63) |
4.57 | 1487 | 42 833 612 |
< 18.5 18.5–25 ≥ 25 |
CSS 2.17 (1.16–4.08) 1 0.66 (0.45–0.96) |
radical partial |
age, gender, anemia ASA score, cell type, tumor grade, T, N and M stage, | 7 |
| Teng et al 2014 China |
mean 53.4 (41–65.8) |
5 | 378 | 11 349 |
< 18.5 ≥ 18.5 |
CSS 5.812 (1.124–30.059) NA |
radical partial |
tumor necrosis, sarcomatoid change, high Ki-67 expression level, advanced Fuhrman grade, and T stage | 8 |
| Lee et al 2010 Korea |
mean 54.9 (12–90) |
2.3 | 2981 | Na | < 30 ≥ 30 |
CSS NA 0.599 (0.146–2.456) |
radical partial |
age, sex, T stage, and Fuhrman’s grade | 6 |
| Haferkamp et al 2008 Germany |
median 61.6 (14.6–89.0) |
5.3 | 780 | 10 245 361 141 |
< 18.5 18.5–25 25–30 ≥ 30 |
CSS 4.27 (1.47–12.4) 1 1.00 (0.75–1.3 1.11 (0.74–1.65) |
radical | age, gender, Karnofsky PS, tumour stage Fuhrman grade, histological type and BMI |
7 |
| Schrader et al 2009 Germany |
mean < 25 64.9 (53.7–76.1) ≥ 25 62.6 (52.2–73) |
5.48 | 771 | 4 239 356 172 |
< 18.5 18.5–25 25–30 ≥ 30 |
CSS NA 1 0.65 (0.50–0.86) 0.60 (0.42–0.84) |
radical nephron–sparing laparoscopically |
tumor grade, stage, lymphatic metastasis, pulmonary/visceral metastasis, histological subtype, age, sex, and tumor–related symptoms at presentation | 7 |
| Kamat et al 2004 US |
mean 58.3 (19–85) |
9.75 | 400 | 125 275 |
< 25 ≥ 25 |
CSS 1 0.46 (0.24–0.85) |
Not available | Age, stage and grade |
7 |
| Jeon et al 2010 Korea |
54.7 (20–83) | 6.41 | 1017 | 363 526 128 |
< 23 23–27.5 ≥ 27.5 |
CSS 1 0.67 (0.46–0.98) 0.42 (0.19–0.89) OS 1 0.71 (0.51–0.99) 0.41 (0.21–0.80) |
radical nephron sparing |
age, BMI, pathological T stage, regional lymph node involvement, distant metastases, tumor size and sarcomatoid change | 7 |
| Choi et al 2013 Korea |
54 | 3.67 | 1543 | 41 448 385 669 |
< 18.5 18.5–23 23–25 ≥ 25 |
CSS 2.13 (0.84–5.36) 1 1.00 (0.63–1.60) 0.47 (0.29–0.77) OS 2.05 (0.85–4.91) 1 1.02 (0.68–1.53) 0.45 (0.29–0.68 |
radical partial |
Age, sex, WL, stage, size, NT, HS, grade Symptom, ESR | 7 |
| Komura et al 2011 Japan |
62.4 (21–86) | 4.17 | 170 | 83 87 |
< 22 ≥ 22 |
CSS 1 0.091 (0.009–0.904) |
radical partial |
Mode of presentation, ECOG PS, C–reactive protein, HS, grade, microvascular | 6 |
| Cho et al 2009 Korea |
56 | 4.33 | 299 | < 23 23–25 ≥ 25 |
CSS 1 0.510 (0.195–1.329) 0.200 (0.045–0.884) |
radical nephron– sparing |
Capscular invasion, stage |
7 | |
| Donat et al 2006 US |
61 (52–70) | 9.17 | 1159 | 1137 278 472 387 |
< 25 25–30 ≥ 30 |
OS 1 0.69 (0.48, 1.00) 0.90 (0.62, 1.30) |
radical partial |
age type of operation, systemic symptoms at presentation |
7 |
| Steffens et al 2013 European |
62.3 (20–90) | 4.72 | 2030 | 700 885 445 |
<25 25–30 ≥ 30 |
CSS 1 0.71 (0.57–0.87) 0.94 (0.73–1.21) |
radical partial |
Age and sex, tumor stage, differentiation grade, histopathological subtape, lymphogenous/visceral metastasis | 6 |
| Ha et al 2011 Korea |
TLRN: 56.5 (44.3–68.7) RLRN: 54.8 (43.0–55.6) |
2.59 | 580 | < 23 23–24.9 ≥ 25 |
OS 1.000 0.342 (0.093–1.263) 0.359 (0.113–1.139) |
TLRN RLRN |
age, sex, NT, ECOG PS, grade, stage | 7 | |
| Lee et al 2015 Korea |
55.9 (43.5–68.3) |
3.17 | 2769 | 853 1916 |
18.5–23 ≥ 23 |
CSS 1 0.611 (0.441–0.847) |
Not available | Age, gender, symptoms at presentation, Tumor size, T stage, Fuhrman’s grade, Histologic subtype. |
7 |