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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Allergy Clin Immunol Pract. 2017 Sep 22;6(3):844–852. doi: 10.1016/j.jaip.2017.08.007

Table 3.

Odds Ratios for Factors Associated with Very Poorly Controlled Asthma at 6 months, unadjusted.

Asthma Control Status at Six Months Outcome: Asthma VPC
NWC or WC
N=114 (53.8%)
VPC
N=98 (46.2%)
OR (95% CI), p-valuea
Child age @ baseline: <6 years 44.6 50.5% 1.27 (0.74–2.17), p=0.397
Child Gender: Female 34.5% 37.1% 1.12 (0.64–1.96), p=0.695
Atopic: + >=1 allergen test 77.8% 87.2% 1.95 (0.88–4.29), p=0.098
# + allergen tests, mean (SD) 4.4 (3.4) 4.6 (3.3) 1.02 (0.94–1.11), p=0.649
Allergic Rhinitis: YesҰ 52.6% 74.2% 2.59 (1.44–4.65), p=0.001
# PCP visits past 3 monthsҰ: P=.004
  None 45.6% 33.7% Reference
  One 40.4% 32.7% 1.10 (0.59–2.05), p=0.774
  Two or more 14.0% 33.7% 3.25 (1.55–6.81), p=0.002
ICS use (past 2 weeks) parent report: P=.911
  None 23.4% 24.5% Reference
  Monotherapy 39.6% 41.5% 1.00 (0.49–2.03), p=0.996
  Combination Therapy 36.9% 34.0% 0.88 (0.43–1.83), p=0.736
How long a controller medication inhaler lasts? P=.449
  Less than 1 month 55.8% 63.1% 1.78 (0.72–4.38), p=0.211
  1–2 months 27.4% 26.2% 1.50 (0.56–4.07), p=0.421
  >=3 months 16.8% 10.7% Reference
Caregiver worried about medication side effects (Yes)Ұ: 27.7% 42.7% 1.95 (1.10–3.47), p=0.024
Season of enrollmentҰ: P=.041
Fall 27.0% 46.8% 2.93 (1.30–6.60), p=0.009
Winter 35.1% 14.9% 0.72 (0.29–1.77), p=0.472
Spring 14.4% 24.5% 2.88 (1.14–7.23), p=0.025
Summer 23.4% 13.8% Reference
Season of six month follow-upҰ: P=.001
  Fall 17.7% 26.8% 3.17 (1.39–7.22), p=0.006
  Winter 20.4% 10.3% 1.06 (0.41–2.72), p=0.904
  Spring 27.4% 46.4% 3.54 (1.69–7.42), p=0.001
  Summer 34.5% 16.5% Reference
Ұ

P<.05, distributional difference between VPC patients and those NWC or WC significant based on Chi-square test for categorical factors and independent t-test for continuous factors. OR=Odds ratio based on GEE with binomial distribution specified (continuous variables ~ odds of very poorly controlled disease per one unit increase)