Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 15;9:373. doi: 10.3389/fimmu.2018.00373

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Simoni, Delgado, Ruer-Laventie, Bouis, Soley, Heyer, Robert, Gies, Martin, Korganow, San Martin and Soulas-Sprauel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Ig production in Trib1-ROSA Mb1Cre compared to Trib1-ROSA control mice, at basal level and after immunization with a T-dependent antigen. (A) Sera from 6-month-old Trib1-ROSA and Trib1-ROSA Mb1Cre mice were collected and total IgM and IgG, IgG1, IgG2b, and IgG3 concentrations were determined by ELISA. Each dot represents the result for one animal. (B) Trib1-ROSA mice (n = 7) and Trib1-ROSA Mb1Cre mice (n = 6) were immunized with ovalbumin (OVA) associated with alum hydroxide at days 0, 10, and 20. Serum was collected at days 20 and 30, then anti-OVA IgM, IgG, and IgG1 titers were measured by ELISA (*p < 0.05, **p < 0.001, Mann and Whitney test).