Figure 3.
Differential upregulation of D2 receptors in white blood cells by dopamine. (A) Percent expression of D2-subtype dopamine receptors (D2Rs) in blood lymphocytes vs monocytes following a 1-h incubation with DA at varying concentrations. While the % of monocytes expressing D2Rs was not affected by DA, the % of lymphocytes expressing D2Rs was significantly enhanced at 1.0 and 10 µM DA. (B) While the total expression of D2Rs in monocytes was not affected by DA, the total expression of D2Rs in lymphocytes was significantly enhanced at 1.0 and 10 µM DA. Asterisks *, *** indicate significance levels p < 0.05 and p < 0.001, respectively.