Table 2.
Comparison of the factors related to tumor recurrence/persistence.
| Items | Non-recurrence (n = 64) | Recurrence/persistence (n = 22) | P-value |
|---|---|---|---|
| Age (mean ± SD, years) | 52.3 ± 12.6 | 53.5 ± 12.0 | 0.708 |
| Sex | 0.999 | ||
| Female | 39 (60.9) | 14 (63.6) | |
| Male | 25 (39.1) | 8 (36.4) | |
| Type of thyroid surgery | 0.755 | ||
| Total thyroidectomy | 57 (89.1) | 21 (95.5) | |
| Hemithyroidectomy | 6 (9.4) | 1 (4.5) | |
| Subtotal thyroidectomy | 1 (1.6) | 0 (0) | |
| Size of primary MTC (mm) | 15.9 ± 14.4 | 19.7 ± 11.1 | 0.263 |
| Location of primary MTC | 0.999 | ||
| Right | 44 (68.8) | 15 (68.2) | |
| Left | 19 (29.7) | 7 (31.8) | |
| Isthmus | 1 (1.6) | 0 (0) | |
| T stage | <0.001 | ||
| T1a | 20 (31.3) | 2 (9.1) | |
| T1b | 25 (39.1) | 4 (18.2) | |
| T2 | 8 (12.5) | 2 (9.1) | |
| T3 | 11 (17.2) | 14 (63.6) | |
| T4a | 0 (0) | 0 (0) | |
| N stage | <0.001 | ||
| Nx (unknown) | 3 (4.7) | 0 (0) | |
| N0 | 36 (56.3) | 2 (9.1) | |
| N1a | 16 (25) | 4 (18.2) | |
| N1b | 9 (14.1) | 16 (72.7) | |
| M stage | <0.001 | ||
| Mx (unknown) | 6 (9.4) | 9 (40.9) | |
| M0 | 58 (90.6) | 12 (54.5) | |
| M1 | 0 (0) | 1 (4.5) | |
| Multiplicity/bilaterality | 0.013 | ||
| Solitary | 56 (87.5) | 14 (63.6) | |
| Satellite MTC in the ipsilateral lobe | 2 (3.1) | 4 (18.2) | |
| Satellite MTC in the contralateral lobe | 0 (0) | 1 (4.5) | |
| Satellite MTC in both lobes | 6 (9.4) | 3 (13.6) | |
| Interval of the last follow-up US (mean ± SD, months) | 74.7 ± 24.2 | 89.9 ± 23.8 | 0.013 |
| Session number of the last follow-up US | 6.4 ± 2.8 | 8.7 ± 4.0 | 0.005 |
Data presented in parentheses are percentage of each item.
MTC, medullary thyroid carcinoma; US, ultrasonography.