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. 2018 Mar 21;8:4971. doi: 10.1038/s41598-018-23366-7

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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COG categories for Mga-regulated genes observed in THY and C media. A comparison of differentially expressed (DE) genes in various cluster of orthologous genes (COG) categories from THY (open bars) versus C media (crossed bars) of the GAS 5448 ∆mga 5448.930 mutant at late logarithmic growth when compared to the WT 5448. Bar length depicts the number of DE genes either down regulated (red) or up regulated (green) at p value of ≤0.05 with the total number of down and up regulated genes shown.