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. 2018 Mar 15;9:203. doi: 10.3389/fphys.2018.00203

Table 2.

Plasma IL-6 and IL-10 concentrations before and after control, moderate- and higher-intensity exercise in higher and lower fit groups.

Time point (min) P-value
Baseline 0 Post 20 Post 90 Post Time Protocol Group Interactions
Interleukin-6 (pg/ml)
Lower fit Control 1.83 (1.37–2.29) 2.03 (1.61–2.46)a 1.93 (1.43–2.44) 2.15 (1.62–2.68) Protocol*Time: 0.89
Protocol*Group: 0.06
Time*Group: 0.34
Protocol*Time*Group: 0.74
Moderate-intensity 1.95 (1.46–2.44) 2.47 (1.91–3.03)a 2.08 (1.61–2.56) 2.59 (1.87–3.31)
Higher-intensity 2.15 (1.48–2.81) 2.27 (1.75–2.79)a 2.21 (1.53–2.90) 2.22 (1.72–2.72) 0.02 0.11 0.02
Higher fit Control 3.53 (2.24–4.82) 3.70 (2.38–5.01)a 3.48 (1.92–5.03) 3.53 (2.26–4.79)
Moderate-intensity 3.10 (1.93–4.28) 3.88 (2.55–5.21)a 3.58 (2.15–5.02) 3.26 (1.60–4.91)
Higher-intensity 3.56 (2.29–4.84) 4.14 (2.83–5.46)a 4.01 (2.50–5.51) 3.96 (2.51–5.41)
Interleukin-10 (pg/ml)
Lower fit Control 1.59 (1.06–2.13) 1.71 (1.19–2.24)a 1.54 (1.06–2.02) 1.58 (1.11–2.04) Protocol*Time: 0.83
Protocol*Group: < 0.01
Time*Group: 0.12
Protocol*Time*Group: 0.87
Moderate-intensity 2.05 (1.11–3.00)b 2.19 (0.97–3.41)ab 1.97 (0.99–2.95)b 2.31 (0.85–3.78)b
Higher-intensity 1.59 (1.17–2.01) 1.70 (1.26–2.14)a 1.50 (1.04–1.97) 1.62 (1.21–2.02) <0.01 0.02 0.45
Higher fit Control 2.51 (1.00–4.03) 2.50 (0.83–4.13)a 2.56 (0.57–4.54) 2.19 (0.72–3.65)
Moderate-intensity 2.32 (0.82–3.81) 2.71 (0.80–4.62)a 2.54 (0.73–4.35) 2.20 (0.71–3.70)
Higher-intensity 2.40 (0.76–4.03) 2.79 (0.97–4.62)a 2.75 (0.41–5.09) 2.38 (0.70–4.07)

Interleukin-6 (IL-6) and IL-10 responses to seated control, moderate-intensity continuous and higher-intensity intermittent exercise protocols. Data presented are from plasma samples taken before, immediately after, 20 and 90 min post-protocol. All data are mean (95% confidence interval).

a

Higher at 0 min post-protocol compared with baseline (P < 0.05).

b

Higher during moderate-intensity visit compared with higher-intensity and control visits in lower fit group only (P < 0.05). P-values in bold represent a significant difference (P < 0.05).