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. 2018 Mar 15;11:57. doi: 10.3389/fnmol.2018.00057

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Copyright © 2018 Bruce, Gorkhali, Given, Coates, Boyle, Macklin and Eckel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LPL is involved in lipid and lipoprotein uptake in microglia. (A) Intracellular uptake of radiolabeled synthetic lipid vesicles containing 50 or 100 μM Triolein Tg. (B) Uptake/phagocytosis of 1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate (DiI) labeled synthetic chylomicrons (SC) and phospholipid liposomes (PLs; N = 3 per group). (C–F) Expression of scavenger and lipoprotein receptors in BV-2 202 vs. 553 cells (N = 4 per group). **P < 0.01 vs. CONT. ***P < 0.001 vs. CONT.