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. 2018 Mar 15;11:57. doi: 10.3389/fnmol.2018.00057

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Copyright © 2018 Bruce, Gorkhali, Given, Coates, Boyle, Macklin and Eckel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CM from LPL KD cells prevents normal remyelination processes. Ex vivo cerebellar slices were demyelinated by overnight treatment (17 h) with lysolecithin. The next day slices were incubated with either standard slice media, or CM and allowed to recover for 7 days.