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. 2018 Mar 21;8:4964. doi: 10.1038/s41598-018-23321-6

Table 3.

Percentage of our computational experiments of drug combinations that can be considered synergistic, additive or antagonistic based on the results of the standard and CISNE methods, and for different values of E[m].

E[m] method CI(fa = 0.5) < 0.8 (synergistic) 0.8 < CI(fa = 0.5) < 1.2 (additive) 1.2 < CI(fa = 0.5) (antagonistic)
0.5 standard 13.47% 66.54% 19.99%
CISNE 11.99% 69.86% 18.15%
1 standard 12.87% 67.69% 19.44%
CISNE 3.73% 88.56% 7.72%
2 standard 15.11% 63.06% 21.84%
CISNE 0.58% 97.37% 2.05%