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. 2018 Mar 21;9:1179. doi: 10.1038/s41467-018-03205-z

Fig. 2.

Fig. 2

Schematic representation of the evolutionary model for the steps in the spread of the mcr-1 gene. (1) The formation of the original composite transposon, followed by (2) transposition between plasmid backgrounds and (3) stabilization via loss of ISApl1 elements before (4) plasmid-mediated spread