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. 2017 Dec;14(12):737–742. doi: 10.11909/j.issn.1671-5411.2017.12.003

Table 1. Demographics, baseline clinical parameters and pharmacological treatment of the two groups of patients.

SRs (59) Non-SRs (142) Total (201) P value
Demographic
 Male gender 34 (57.6%) 95 (66.9%) 129 (64.2%) 0.212
 Age, yrs 58.8 ± 10.6 57.3 ± 11.4 57.7 ± 11.2 0.390
Etiology
 NICM 53 (89.8%) 126 (88.7%) 179 (89.1%) 0.820
 ICM 6 (10.2%) 16 (11.3%) 22 (10.9%)
NYHA Class
 II 17 (28.8%) 33 (23.2%) 50 (24.9%) 0.206
 III 38 (64.4%) 83 (58.5%) 121 (60.2%) 0.170
 IV 4 (6.8%) 26 (18.3%) 30 (14.9%) 0.037
UCG and ECG variables
 LVEF, % 32.2 ± 8.5 27.4 ± 7.3 28.8 ± 8.3 < 0.001
 LVESV, mL 156.5 ± 49.7 205.0 ± 74.5 190.6 ± 71.6 < 0.001
 LVEDV, mL 228.4 ± 58.9 278.3 ± 85.1 263.7 ± 81.4 < 0.001
 LAD, mm 41.3 ± 7.1 44.8 ± 7.0 43.7 ± 7.2 0.002
 FMR 1.3 ± 0.8 1.6 ± 0.8 1.5 ± 0.8 0.046
 QRS duration, ms 164.5 ± 16.0 161.5 ± 19.3 162.4 ± 18.4 0.289
 LBBB 56 (94.9%) 127 (89.4%) 183 (91.0%) 0.215
 De novo 55 (93.2%) 138 (97.2%) 193 (96.1%) 0.191
 CRT-D 32 (54.2%) 80 (56.3%) 112 (55.7%) 0.636
Co-morbidity
 Chronic AF 9 (15.3%) 19 (13.4%) 28 (13.9%) 0.727
 Hypertension 19 (32.2%) 35 (24.6%) 54 (26.9%) 0.456
 Diabetes mellitus 9 (15.3%) 31 (21.8%) 40 (19.9%) 0.285
 Medication
 Diuretics 56 (94.9%) 141 (99.3%) 197 (98.0%) 0.077
 ACEI/ARB 52 (88.1%) 98 (69.0%) 150 (74.6%) 0.005
 β-Blockers 55 (93.2%) 139 (97.9%) 194 (96.5%) 0.100
 Nitrates 20 (33.9%) 44 (31.0%) 64 (31.8%) 0.686
 Class III 11 (18.6%) 29 (20.4%) 40 (19.9%) 0.774
Antiarrhythmics
 Spironolactone 56 (94.9%) 130 (91.5%) 186 (92.5%) 0.408
 Digoxin 9 (15.9%) 30 (21.2%) 39 (19.4%) 0.511
 Anticoagulants 7 (11.9%) 12 (8.5%) 39 (9.5%) 0.221

Data given as n (%) or mean ± SD. AF: atrial fibrillation; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CRT-D: cardiac resynchronization therapy-defibrillator; ECG: electrocardiographic; FMR: functional mitral regurgitation; ICM: ischemic cardiomyopathy; LAD: left atrial diameter; LBBB: left bundle branch block; LVEDV: left ventricular end-diastolic volume; LVEF: left ventricular ejection fraction; LVESV: left ventricular end-systolic volume; NICM: non-ischemic cardiomyopathy; NYHA class: New York Heart Association functional class; Non-SRs: non-super responders; SRs: super-responders; UCG: ultrasonic cardiogram.