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. 2018 Mar 15;35(6):842–853. doi: 10.1089/neu.2017.5184

FIG. 2.

FIG. 2.

Body weight dynamics after prolonged rapamycin (RAP) treatment and spinal cord injury (SCI). The RAP treatment prevented weight gain in both naïve and SCI rats. (A) The RAP prevented the normal increase in body weight over time in naïve, vehicle-treated rats. (B) After SCI, vehicle-treated rats started to regain weight by 16 days post-injury (DPI), whereas RAP-treated rats lost significantly more weight by 10 DPI and failed to approach pre-injury body weights. n = 3 naïve + vehicle; n = 3 naïve + RAP (3 mg/kg); n = 7 SCI + vehicle; n = 7 SCI + RAP (3 mg/kg). Symbols are means ± standard deviation. *p ≤ 0.05, vehicle vs. RAP treatment.