Table 3. Frequencies of MTHFR gene polymorphisms in the mothers of the children with CHD.
Genotype | Control, n (%) | Case, n (%) | χ2 value | P | OR (95% CI) |
---|---|---|---|---|---|
CC | 71 (30.0) | 50 (14.4) | – | – | – |
CT | 108 (45.6) | 156 (45.1) | – | – | – |
TT | 58 (24.4) | 140 (40.5) | 15.33 | <0.0001 | 2.097 (1.455–3.024) |
MTHFR, methylenetetrahydrofolate reductase; CHD, congenital heart disease.