Table 4. Frequencies of the MTHFR gene 677 C>T polymorphism in the fathers of the children with CHD.
Genotype | Control, n (%) | Case, n (%) | χ2 value | P | OR (95% CI) |
---|---|---|---|---|---|
CC | 66 (27.8) | 100 (29.0) | – | – | – |
CT | 115 (48.6) | 154 (44.5) | – | – | – |
TT | 56 (23.6) | 92 (26.5) | 0.5 | 0.48 | 1.171 (0.798–1.717) |
MTHFR, methylenetetrahydrofolate reductase; CHD, congenital heart disease.