Table 1. Airway pathological measurement in each group.
Index | OVA | OVA + si-PTEN | NS | NS + si-PTEN |
---|---|---|---|---|
WAi/Pi (ìm) | 13.39±2.40* | 17.82±2.95*# | 5.32±0.74 | 14.73±2.69* |
WAm/Pi (ìm) | 6.62±0.98* | 9.96±1.25*# | 1.26±0.33 | 7.08±1.08* |
N/Pi/ (mm) | 34.99±5.22* | 39.03±6.86*# | 12.91±1.94 | 35.74±5.61* |
Sα/Pb (ìm) | 5.29±0.54* | 8.65±0.75*# | 2.35±0.39 | 5.48±0.68* |
*, P<0.05 compared with the NS group; #, P<0.05 compared with the OVA group. OVA, ovalbumin; siRNA, small interference RNA; PTEN, phosphatase and tensin homolog; NS, normal saline; Pi, inner perimeter of the bronchial wall; WAi, inner area of the bronchial wall; WAm, airway smooth muscle area; N, number of smooth muscle nuclei; Sα, area of alpha smooth muscle actin (α-SMA+); Pb, bronchial basement membrane perimeter.