Table 1. Characteristics of the study population.
Parameter | All patients (N=74) | Dexmedetomidine group (N=31) | Midazolam group (N=43) |
---|---|---|---|
Gender (male/female) | 42/32 | 18/13 | 24/19 |
Age (year) | 58.8±12.2 | 57.2±11.8 | 59.9±12.5 |
Height (cm) | 168.20±9.04 | 168.61±9.09 | 167.91±9.10 |
Weight (kg) | 66.30±9.55 | 67.55±9.19 | 65.40±9.81 |
APACHEII score | 16.84±4.62 | 16.71±4.79 | 16.93±4.54 |
Indications for fiberoptic bronchoscopy (examination diagnosis/bronchoalveolar lavage) | 24/50 | 10/21 | 14/29 |
Remedial sedation by propofol (yes/no) | 37/37 | 22/9 | 15/28 |
Total sedation time (min) | 25.20±4.35 | 27.87±4.10 | 23.28±3.44 |
Time of FFB (min) | 18.37±3.78 | 19.77±3.79 | 17.36±3.48 |
Satisfaction score of the bronchoscopists | 7.36±1.88 | 7.03±2.07 | 7.60±1.71 |
Cough (yes/no) | 29/45 | 17/14 | 12/31 |
Nausea (yes/no) | 13/61 | 5/26 | 8/35 |
Bronchospasm (yes/no) | 33/41 | 19/12 | 14/29 |
Tachycardia (yes/no) | 26/48 | 11/20 | 15/28 |
Bradycardia (yes/no) | 7/67 | 3/28 | 4/39 |
Arrhythmia (yes/no) | 6/68 | 3/28 | 3/40 |
Oxygen desaturation (yes/no) | 26/48 | 15/16 | 11/32 |
Hypotension (yes/no) | 12/62 | 5/26 | 7/36 |
Hypertension (yes/no) | 13/61 | 6/25 | 7/36 |
APACHE II score, acute physiology and chronic health evaluation II score; Satisfaction score, consistency between respiratory therapist and nurse on the comments of the bronchoscopists. FFB, flexible fiberoptic bronchoscopy.