Table 1.

Demographic and clinical information of patients with bipolar disorder during depressive episodes (BD) and healthy controls (HC).

	BD (n=25)	HC (n=31)	Statistical tests
Age (mean±SD)	28.44±5.6	27.65±6.0	t= −0.50, df=54, p=0.615
Gender- n females(%)	18 (72.0%)	16 (51.6%)	χ2=2.41, df=1, p=0.120
BD subtype- n Bipolar II (%)	16 (64.0%)	–	–
Duration of illness (months; mean±SD)	35.66±20.4	–	–
Medication-free N (%)	22 (88.0%)	–	–
Treatment-naïve N (%)	18 (72.0%)	–	–
Previous psychosis	3 (12%)	–	–
Family history mood disorders	9 (36.0%)	–	–
Tobacco use	4 (16%)	4 (16%)	n.s.
BMI baseline	29.3±5.41	27.45±4.01	n.s.