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. 2018 Mar 21;9:71. doi: 10.1186/s13287-018-0813-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Gas5 induces iPSC reprogramming efficiency. a Endogenous expression of Gas5 in mouse embryonic fibroblasts (MEFs) and reprogrammed induced pluripotent stem cells (iPSCs). b,c Morphology and quantitative analysis of Oct4-GFP⁺ cells during Gas5 knockdown (KD) and control (NC) MEF reprogramming. d Alkaline phosphatase staining results in Gas5 KD-MEF-formed iPSC clones and control MEF-formed iPSC clones. e Endogenous expression of pluripotent markers Oct4, Sox2, and Nanog during Gas5 KD MEF- and control MEF-mediated reprogramming. **P < 0.01, t test, n = 3. Error bars represent SEM of the indicated experiment replicates