Table 1.
Descriptive findings of 7 studies reporting on rTMS as a treatment for depression in PD
| Reference | Type | Improvement | Number | Mean age (years) | Sessions/stimulation | Time Period (days) | Primary rTMS Site | rTMS Side | Follow-up | Depression Scales |
|---|---|---|---|---|---|---|---|---|---|---|
| Brys (2016) [18] | Multi-center | No | 61 | 63 | 10/1000 to 2000 at 10 Hz | 14 | DLPFC | L | 30 days | HAM-D |
| Dragasevic (2002) [22] | Prospective | Yes | 10 | 60 | 10/100 at 0.5 Hz | 10 | DLPFC | B | 21 days 30 days |
HAM-D BDI |
| Epstein (2007) [23] | Prospective | Yes | 14 | 62 | 20/1000 at 10 Hz | 20 | DLPFC | L | 6 weeks | HAM-D BDI |
| Fregni (2004) [24] | Sham-controlled | Yes | 42 | 65 | 10/40 at 15 Hz | 14 | DLPFC | L | 2 weeks 8 weeks |
HAM-D BDI |
| Makkos (2016) [25] | Randomized sham-controlled |
Yes | 46 | 66 | 10/600 at 5 Hz | 10 | M1 | B | 1 day 30 days |
MADRS BDI |
| Pal (2010) [26] | Randomized sham-controlled |
Yes | 22 | 68 | 10/600 at 5 Hz | 10 | DLPFC | L | 1 day 30 days |
MADRS BDI |
| Torres (2015) [27] | Retrospective | Yes | 45 | 63 | 14/1000 at 10 Hza | 21 | PFC | B | 30 day | HAM-D BDI |
DLPFC dorsolateral prefrontal cortex, M1 motor cortex, PFC prefrontal cortex, L left, B bilateral
a1000stim at 10 Hz for PFC; 900 stim at 1 Hz for M1