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. 2018 Mar 21;8:22. doi: 10.1186/s13578-018-0220-8

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Scheme of the chemical surface composition. The silicon–titanium (Ti) substrates were modified by amino functionalization with plasma polymerized allylamine (Ti + PPAAm) as well as immobilization of a bioactive collagen type-I layer (Ti + Col). These modifications were compared with bare Ti substrates and tissue culture plastic (IBIDI)