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. 2018 Mar 2;9:326. doi: 10.3389/fimmu.2018.00326

Table 1.

Probiotics for the bovine host.

Strain Viability Route Host Effects Reference
Lactobacillus acidophilus LAC-300 Viable Oral Holstein calves Increase in body weight gain. Improvement in fecal scores (11)
Bifidobacterium pseudolongum M-602 Viable Oral Holstein calves Increase in body weight gain. Improvement in fecal scores (11)
Bifidobacterium thermophilum S-501, Lactobacillus acidophilus LAC-300, and Enterococcus faecium FA-5 Viable Oral Holstein calves No effect on body weight gain was observed. Reduction of diarrhea (11)
Saccharomyces cerevisiae, Lactobacillus acidophilus, Bifidobacterium bifidum, Streptococcus termophilus, and Aspergillus niger Viable Oral Holstein calves Improvement in daily live weight gain and feed efficiency ratio. Reduction of diarrhea (12)
Lactobacillus rhamnosus GG Viable Oral Holstein calves The probiotic strain survived the gastrointestinal transit. No beneficial effect was recorded (13, 14)
Saccharomyces boulardii Viable Oral Holstein bull calves Treated animals consumed more grain, had increased weight gain, and increased plasma glucose concentrations. Days with diarrhea were reduced (15)
Lactobacillus acidophilus 15 Viable Oral buffalo calve (1 day to 31 weeks) Weight gain was improved and feed: gain ratio was reduced (16)
Multispecies probiotic preparation: Lactobacillus acidophilus W55, Lactobacillus salivarius W57, Lactobacillus paracasei W56, Lactobacillus plantarum W59, Lactococcus lactis W58, and Enterococcus faecium W54 Viable Oral Male Holstein-Friesian calves Probiotics enhanced growth rate and average daily gain and feed efficiency were significantly improved. Modest effect on diarrhea (17)
Calf-specific multistrain probiotic preparation (six lactobacilli strains) Viable Oral Male Holstein-Friesian calves Probiotics enhanced growth rate and average daily gain and feed efficiency were significantly improved. Treatment reduced the incidence of diarrhea and the fecal counts of coliforms (17)
Lactobacillus casei subsp. casei JCM1134T and Dextran Viable Oral Holstein dairy calves Increase the milk production (18)
Lactobacillus acidophillus, Bifidobacterium bifidum, and Enterococcus faecium Viable Oral Holstein calves Significant reduction of diarrhea but no effect on mastitis (19)
Bacillus subtilis natto Viable Oral Male Holstein calves Increased average daily gain and feed efficiency. No difference in serum IgE, IgA, and IgM, whereas serum IgG and IFN-γ were higher in probiotic-treated than in the controls. (20)
Lactobacillus plantarum 220, Enterococcus faecium 26, and Clostridium butyricum Miyari Viable Oral Holstein bull calves Increased the numbers of CD282+ monocytes, CD3+ T cells and CD4+, CD8+, and WC1+ γδ T cell in blood. Increment of production of IL-6, INF-γ, and TNF-α were also observed (21)
Faecalibacterium prausnitzii 34, Faecalibacterium prausnitzii 35, Faecalibacterium prausnitzii 1S, and Faecalibacterium prausnitzii 2S Viable Oral Preweaned dairy Holstein heifer calves Decreased the incidence of severe diarrhea and related mortality rate, while increasing weight gain (22)
Lactobacillus plantarum GF103 Viable Oral Male Holstein calves No significant differences were observed in dry matter intake or average daily gain, but the feed conversation ratio was improved. Treatment improved mitogen-induced lymphocyte proliferation (23)
Kefir Viable Oral Female Holstein calves calves Kefir intake improved fecal scores and reduced days with diarrhea during the first 2 weeks of life. No effect on weight gain (24)
Milk fortified with symbiotic complex containing prebiotics (mannan-oligossacharides) and probiotics (Lactobacillus acidophilus, Enterococcus faecium, Bacillus subtilis, Saccharomyces cerevisiae) Viable Oral Female Holstein heifer calves Symbiotic did not affect weight gain or feed efficiency of calves but it improved fecal scores (25)