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Factors Contributing to Increased PVR in PH
| Pulmonary Vascular Disease | Cardiac Disease | Lung Disease |
|---|---|---|
| High tone and reactivity | RV dysfunction | Hypoxemia |
| Hypertensive vascular remodeling | Impaired LV contractility | Hyperinflation |
| Decreased vascular growth | LV diastolic dysfunction | Atelectasis |
| Systemic-to-pulmonary collateral vessels | left-to right-shunt lesions | Hypercarbia |
| Pulmonary vein stenosis |
RV: right ventricular; LV: left ventricular
