Table 1.
Two-bottle choice tests of T1R3 WT and KO mice: Compounds and mice tested
| Test solution | Cohort and order | Group sizes | ||
|---|---|---|---|---|
| Common name | Formula | T1R3 WT | T1R3 KO | |
| Disodium phosphate | Na2HPO4 | 6c | 3 M, 9 F | 2 M, 8 F |
| Diammonium phosphate | (NH4)2HPO4 | 1b | 12 F | 10 F |
| Disodium pyrophosphate | Na2H2P2O7 | 3c, 6e | 7 M, 13 F | 7 M, 13 F |
| Trisodium pyrophosphate | Na3HP2O7 | published | 11 M, 16 F | 11 M, 16 F |
| Tetrasodium pyrophosphate | Na4P2O7 | 6f, 7c | 7 M, 15 F | 7 M, 12 F |
| Tetrapotassium pyrophosphate | K4P2O7 | 1a | 12 F | 10 F |
| Pentasodium tripolyphosphate | Na5P3O10 | 2a, 3b | 14 M, 4 F | 12 M, 5 F |
| Sodium acetate | C2H3NaO2 | 4b, 6b, 7b | 12 M, 26 F | 9 M, 19 F |
| Sodium propionate | C3H5NaO2 | 3a, 6d | 7 M, 13 F | 7 M, 13 F |
| Sodium gluconate | C6H11NaO7 | 4a, 6a, 7a | 12 M, 26 F | 9 M, 19 F |
| Seven 32 mM salts | — | 5a, 8a | 9 M, 13 F | 8 M, 12 F |
“Cohort and order” identifies which batches of mice were tested and with which compounds. For example, the notation “3c, 6e” for Na2H2P2O7 indicates there were 2 cohorts tested with this compound; it was Cohort 3's 3rd test series and Cohort 6's 5th test series. Group sizes were the sum of M = male, F = female. Most P salts have several names in addition to the one given here. For example, disodium phosphate is also called disodium hydrogen orthophosphate, sodium hydrogen phosphate, and sodium phosphate dibasic. The salts were purchased from Sigma Aldrich except for Na3HP2O7, which was donated by the SPF-Diana Company. The results with Na3HP2O7 have been published previously (Tordoff et al. 2014a).